Chromosome - 1 SNP - rs11206244 Gene Name - DIO1

Basic Information

Genotype Frequency
  • C
  • CT
  • TT
Allele Frequency
  • C
  • T

SNP Expression Description

General SNP Description

This SNP influences the Set Point of the Hypothalamus-Pituitary-Thyroid Axis in patients treated for differentiated Thyroid Carcinoma. This SNP is also associated with the relative levels of free Thyroxine and Triiodothyronine. Furthermore, research also presents the relationship of deiodinase 1 genotype and thyroid function to lifetime history of Major Depression.