Chromosome - 4 SNP - rs17319721 Gene Name - SHROOM3

Basic Information

Genotype Frequency
  • AG
  • GG
  • AA
Allele Frequency
  • G
  • A

SNP Expression Description

General SNP Description

This SNP was significantly associated with glomerular filtration rate (GFR) and albuminuria, which has been found in recent genome-wide studies in patients with Type 2 Diabetes. This gene is involved in regulating cell shape in certain tissue. The function of this gene is involved in controlling cell shape changes in the neuroepithelium during neural tube closure. Disease associated with this gene include the following: Wiskott-Aldrich Syndrome, Metastasis, Tumors, Alzheimer’s Disease and Ocular Albinism.