Chromosome - 14 SNP - rs2236225 Gene Name - MTHFD1

Basic Information

Genotype Frequency
  • AG
  • GG
  • AA
Allele Frequency
  • G
  • A

SNP Expression Description

How does this fit in to your daily life?

Further research is being conducted on this SNP, please consult with your physician before taking any action. Even though current research indicates the possibility that current diseases are associated with this SNP, individuals with this SNP should be aware that this does not necessarily indicate that such diseases are present nor likely.

For more information, please schedule a consult with one of our HealthCoach7 Genetic Specialist.

General SNP Description

This SNP is associated with MHFD1 Gene which encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

 

For more information, please schedule a consult with one of our HealthCoach7 Genetic Specialist.