Chromosome - 5 SNP - rs4704397 Gene Name - PDE8B

Basic Information

Genotype Frequency
  • AG
  • GG
  • AA
Allele Frequency
  • G
  • A

SNP Expression Description

How does this fit in to your daily life?

For more information, please schedule a consult with one of our HealthCoach7 Genetic Specialist.

General SNP Description

The A allele of this SNP is associated with an increase of 0.13 muIU/ml in serum TSH (thyroid-stimulating hormone). Research shows that serum TSH was highest for A/A carriers of this SNP in pregnant women at 28 weeks. This SNP is also associated with Obesity, Hyperthyrotropinaemia, Thyroid Cancer, Myocardial Infarction Autoimmune Disease. This gene functions as a key regulator of many important physiological processes and may also be involved in specific signaling in the thyroid gland. Diseases associated with this gene include Striatal Degeneration, Autosomal Dominant, and Pigmented Nodular Adrenocortical Disease.

For more information, please schedule a consult with one of our HealthCoach7 Genetic Specialist.