Chromosome - 15 SNP - rs6495446 Gene Name - MTHFS

Basic Information

Genotype Frequency
  • CC
  • CT
  • TT
Allele Frequency
  • C
  • T

SNP Expression Description

How does this fit in to your daily life?

Further research is being conducted on this SNP, please consult with your physician before taking any action. Even though current research indicates the possibility that current diseases are associated with this SNP, individuals with this SNP should be aware that this does not necessarily indicate that such diseases are present nor likely.

For more information, please schedule a consult with one of our HealthCoach7 Genetic Specialist.

General SNP Description

The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.

For more information, please schedule a consult with one of our HealthCoach7 Genetic Specialist.